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Lead poisoning is entirely preventable. The key is stopping children from coming into contact with lead and treating children who have been poisoned by lead.

The goal is to prevent lead exposure to children before they are harmed. There are many ways parents can reduce a child’s exposure to lead. The key is stopping children from coming into contact with lead. Lead hazards in a child’s environment must be identified and controlled or removed safely.
Concern about Your Child’s Exposure

If you have any reason to suspect that your child has been exposed to lead contact your health care provider. Your child’s health care provider can help you decide whether to perform a blood test to see if your child has an elevated blood lead level. A blood lead test is the only way you can tell if your child has an elevated lead level. Most children with elevated blood lead levels have no symptoms. The health care provider can recommend treatment if your child has been exposed to lead.

Lead poisoning is entirely preventable. The key is stopping children from coming into contact with lead and treating children who have been poisoned by lead. Learn more about preventing childhood lead poisoning and National Lead Poisoning Prevention Week activities.

Childhood Lead Exposure

Young children often place their toys, fingers, and other objects in their mouth as part of their normal development, this hand-to-mouth activity may put them in contact with lead paint or dust.

The most common sources of lead exposure for children are chips and particles of old lead paint. Although children may be directly exposed to lead from paint by swallowing paint chips, they are more commonly exposed by swallowing house dust or soil contaminated by leaded paint. This happens because lead paint chips become ground into tiny bits that become part of the dust and soil in and around homes. This usually occurs when leaded paint becomes old or worn or is subject to constant rubbing (as on doors and windowsills and wells). In addition, lead can be scattered when paint is disturbed during destruction, remodeling, paint removal, or preparation of painted surfaces for repainting.

Lead, which is invisible to the naked eye and has no smell, may be found in other sources. These sources may be the exposure source for as many as 30% of lead-poisoned children in certain areas across the United States. They include
traditional home health remedies such as azarcon and greta, which are used for upset stomach or indigestion in the Hispanic community
imported candies
imported toys and toy jewelry
imported cosmetics
pottery and ceramics
drinking water contaminated by lead leaching from lead pipes, solder, brass fixtures, or valves and
consumer products, including tea kettles and vinyl miniblinds

Additionally, a variety of work and hobby activities and products expose adults to lead. This also can result in lead exposure for their families. Activities that are associated with lead exposure include indoor firing range use, home repairs and remodeling, and pottery making. “Take-home” exposures may result when people whose jobs expose them to lead wear their work clothes home or wash them with the family laundry. It also may result when they bring scrap or waste material home from work.

Children with attention-deficit/hyperactivity disorder (ADHD) are more likely than other children to engage in criminal activity when they grow older, a U.S. study has found.

The study included more than 10,000 adolescents who were later surveyed in adulthood. It found that youngsters with ADHD were twice as likely to commit theft later in life and were 50 percent more likely to sell drugs.

The findings, believed to be the first evidence of a link between ADHD and criminal activity, were published online Sept. 30 in the Journal of Mental Health Policy and Economics.

“While much research has shown links between ADHD and short-term educational outcomes, this research suggests significant longer-term consequences in other domains, such as criminal activities,” study lead author Jason M. Fletcher, an assistant professor at the Yale School of Public Health, said in a university news release.

“We also found important differences in the association between adult crime and the type of childhood ADHD symptoms — whether hyperactive or inattentive or both,” he said.

Crimes where ADHD is a factor may cost the nation $2 billion to $4 billion a year, estimates have indicated.

Fletcher and colleagues plan to investigate whether drug treatments may reduce the illegal activities associated with ADHD in adulthood. The researchers also plan to study the associations between childhood ADHD symptoms and later employment and earnings.

ADHD, which affects between 2 percent to 10 percent of U.S. schoolchildren, is far more common in males than females. It’s also more prevalent in people who have close relatives with the condition, suggesting a genetic origin, the study authors noted in the news release.

A Central Institutional Review Board (CIRB) for cancer clinical trials that was created by the National Cancer Institute (NCI), part of the National Institutes of Health, in 2001 helps trials start more quickly (just over a month faster, on average) and thus expedite the time from concept to completion of crucial investigational research according to a new finding. This study of the CIRB was performed by scientists at the Veterans Affairs Palo Alto Health Care System (VAPAHCS) and Stanford University School of Medicine, Palo Alto, Calif., with assistance from NCI and appears online October 19, 2009 in the Journal of Clinical Oncology.

Over the past 40 years, more than 1,700 institutions in the United States have enrolled up to 20,000 patients annually in phase III clinical trials coordinated by NCI and have used separate IRBs to monitor research involving patients. Federal regulations require that most NIH-funded clinical trials be monitored by an IRB.

To determine whether a new treatment is safe and more effective than current treatments using clinical trials is a lengthy process that can take up to 10 years and cost more than $1 billion, in some cases. Many researchers have complained that administrative requirements, including IRB oversight, are delaying the release of new treatments. One solution NCI proposed was to form a CIRB to conduct IRB review of large, multi-site oncology trials.

“Mounting a CIRB that is nationwide in scope has been challenging for NCI due to the complexity involved in assuring high-quality protection for study participants while attempting to speed the process,” said Jeffrey Abrams, M.D., associate director of NCI’s Cancer Therapy Evaluation Program. “For all the volunteer reviewers and participating sites, this study provides objective confirmation that a centralized approach significantly improves the overall process for participants in multi-site trials.”

The study assessed whether use of NCI’s CIRB was associated with lower effort, time and cost in processing adult phase III oncology trials, which are the gold-standard of trials for validating whether a therapy becomes a new standard of care. Early phase trials (phase I and II) and pediatric trials were not included in the analysis due to the lower patient enrollment populations required.

Clinical trial sites that are not enrolled with the CIRB must have their local IRB conduct a full board review as they would with any research study. Sites enrolled with the CIRB have their local IRB conduct a facilitated review, which is a review category requiring only that the local IRB chairperson or designee signal acceptance of the CIRB’s review.

To determine whether the CIRB was achieving the hoped-for efficiencies, researchers compared clinical trial review at sites affiliated with the NCI CIRB with the review at unaffiliated sites that used their local IRB. Oncology research staff and IRB staff were surveyed to understand differences in effort, timing and costs of clinical trial review. CIRB affiliation was associated with faster local review (about 34 days) and about six hours less research staff effort. Many clinical trials sponsors value faster and more predictable reviews and often pay commercial, fee- for-service, central IRBs to perform reviews.

Affiliation with NCI’s CIRB was also associated with a savings of $717 per initial review, of which about half was associated with time savings for research staff and the remainder was associated with savings for the IRB staff. Overall, the program resulted in a net cost of $55,000 per month for NCI, but the CIRB could actually save costs if more sites were to use the CIRB. Moreover, this net cost estimate does not include the benefits of bringing new cancer therapeutics to market more quickly.

“Efforts are underway to expand enrollment in the CIRB and to encourage sites to use the CIRB to minimize administrative inefficiencies,” said lead researcher Todd H. Wagner, Ph.D., health economist, VAPAHCS and Stanford University School of Medicine, Palo Alto, Calif., “and based on our research, increased efficiencies and net savings are likely.”

The Veterans Affairs Palo Alto Health Care System (VAPAHCS) comprises three divisions, including a large tertiary care facility. It is affiliated with Stanford University Medical School and provides a full range of patient care services with state-of-the-art technology, as well as education and research. Comprehensive health care is provided through primary care, tertiary care and long-term care in areas of medicine, surgery, psychiatry, physical medicine and rehabilitation, neurology, oncology, dentistry, geriatrics, and extended care. VAPAHCS has 897 operating beds, and is home to a variety of regional treatment centers, including a Spinal Cord Injury Center, a Polytrauma Rehabilitation Center, the Western Blind Rehabilitation Center, a Geriatric Research, Educational and Clinical Center and the National Center for PTSD.

Parents and caregivers who place car seats on beds, kitchen counters and other places outside the car injured 43,000 U.S. children over five years, researchers reported on Monday.

More than 3,400 of the children were injured badly enough to require hospitalization, the researchers told a meeting of the American Academy of Pediatrics.

“Many families learn the importance of strapping an infant car seat into a vehicle, but they do not learn about the dangers of using infant car seats as carriers or placing them on countertops or beds,” Dr. Shital Parikh of Cincinnati Children’s Hospital Medical Center told the meeting.

Most of the children were injured on the head, but they also broke leg and arm bones, he said.

“When parents or caregivers place the infant car seat on top of a table or elevated surface, the infant can wiggle and end up toppling off out of the seat onto the floor, which can lead to severe injuries,” Parikh said in a statement.

“Another accident that can happen is the turning over of the car seat on to a soft surface, which can lead to suffocation.”

Parikh used a Consumer Products Safety Commission database to make his calculations.